Type 1 and type 2 responses toLeishmania major

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Type 1 and type 2 responses to Leishmania major.

Leishmania major is a protozoan parasite that is transmitted to the mammalian host by its sand fly vector when the fly probes in the host's skin for a blood meal and injects the parasite within its saliva. In mice experimentally infected with L. major, outgrowth of CD4 type 1 (Th1) cells leads to resolution of the infection, but outgrowth of type 2 (Th2) cells exacerbates disease. To design an ...

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ژورنال

عنوان ژورنال: FEMS Microbiology Letters

سال: 2002

ISSN: 0378-1097,1574-6968

DOI: 10.1111/j.1574-6968.2002.tb11101.x